Swiss Chems is a well-known name in the research chemical industry, recognized for their commitment to providing high-quality compounds for scientific investigation. Their dedication to maintaining rigorous quality control standards has established them as a trusted source for researchers worldwide.
SR-9011, a synthetic REV-ERB agonist, has captured significant attention in the scientific community due to its potential role in circadian rhythm regulation and metabolic processes. This compound's unique properties make it valuable for researchers studying chronobiology and metabolic pathways.
This comprehensive guide for 2025 examines Swiss Chems' SR-9011, providing researchers with:
- Detailed chemical analysis and mechanisms of action
- Product specifications and quality assurance measures
- Pharmacokinetic properties
- Research applications and considerations
- Storage and handling protocols
The information presented aims to support researchers in making informed decisions about SR-9011 usage in their experimental protocols, backed by Swiss Chems' commitment to scientific advancement through reliable research materials.
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Understanding SR-9011: Chemical Profile and Mechanism of Action
SR-9011 is an important breakthrough in chronobiology research. It has a unique chemical structure of C23H31ClN4O3S and a molecular weight of 479.0 g/mol. Various research databases recognize this compound by different names:
- CHEMBL1961797 (ChEMBL Database ID)
- CAS Number: 1379686-29-9
- Common Name: SR-9011
How SR-9011 Works
The compound acts as a synthetic agonist, showing strong binding affinity for both REV-ERBα and REV-ERBβ nuclear receptors. This interaction with both receptors initiates a series of molecular events that affect cellular metabolism and circadian processes.
Effects on Circadian Rhythm
- Influences core clock gene expression
- Synchronizes cellular metabolic cycles
- Modulates sleep-wake patterns
Effects on Metabolic Pathways
- Enhances lipid metabolism
- Regulates glucose homeostasis
- Affects mitochondrial function
Research shows that SR-9011 achieves these effects by directly binding to REV-ERB proteins. This binding causes changes in the protein's shape, which in turn affects its ability to regulate gene activity. As a result, genes involved in energy expenditure, glucose production, and lipid metabolism are modified.
The compound's ability to target both types of REV-ERB receptors makes it a valuable tool for studying circadian rhythm disorders and metabolic processes in research settings.
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Swiss Chems SR-9011 Product Specifications
Swiss Chems delivers SR-9011 in precisely measured 5mg capsules, with each package containing 60 capsules for a total active ingredient content of 300mg. This standardized dosage format supports accurate research protocols and consistent experimental parameters.
The product arrives in tamper-evident, light-resistant containers designed to protect the compound's integrity. Each bottle features:
- Airtight seal technology
- UV-protective amber glass
- Moisture-resistant packaging
- Clear lot number identification
- Manufacturing date stamp
Storage specifications require maintaining the product at room temperature (20-25°C) in a dry environment, away from direct sunlight. Under these conditions, Swiss Chems SR-9011 maintains its stability for 36 months from the manufacturing date.
The capsule matrix utilizes pharmaceutical-grade excipients to ensure:
- Compound stability
- Protection from oxidation
- Optimal bioavailability
- Consistent dissolution rates
Each batch undergoes rigorous quality control testing before release, with certificates of analysis available upon request. Furthermore, the product's formulation and its effects have been studied extensively, following guidelines such as those outlined in the EMA's scientific guideline for investigating bioequivalence, ensuring that it meets high standards of efficacy and safety.
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Quality Assurance and Testing by Swiss Chems
Swiss Chems ensures top-notch quality control through thorough lab testing protocols. Every batch of SR-9011 goes through several testing stages to confirm the identity of the compound, its purity levels, and structural integrity.
The testing process includes:
- Chromatographic Analysis: HPLC testing confirms compound purity
- Mass Spectrometry: Validates molecular structure
- Heavy Metal Screening: Ensures absence of contamination
- Microbial Testing: Confirms sterility standards
Swiss Chems publishes detailed certificates of analysis on their website for every SR-9011 batch. These certificates display:
- Batch number
- Manufacturing date
- Purity percentage
- Testing methodologies
- Results interpretation
Researchers can request independent verification through HPLC-certified laboratories. Swiss Chems stands behind their quality with a comprehensive refund policy:
- Full reimbursement of product cost
- Coverage of third-party lab testing fees
- Shipping cost refund
- Return shipping compensation
The company maintains strict documentation of their quality assurance processes, allowing researchers to trace product lineage from synthesis to delivery. Their in-house quality control team conducts regular audits of manufacturing facilities and testing procedures to maintain consistency across all batches.
Swiss Chems' commitment to transparency extends to their customer service team, providing detailed testing information upon request. This dedication to quality assurance helps researchers maintain experimental integrity throughout their studies.
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Pharmacokinetics and Metabolism of SR-9011: What Researchers Need to Know
Research data indicates SR-9011 undergoes extensive hepatic metabolism through Phase I and Phase II biotransformation pathways, a process that falls under the broader category of drug metabolism. The primary metabolic processes include:
- Oxidative Metabolism: Cytochrome P450 enzymes catalyze oxidation reactions, producing hydroxylated metabolites
- Conjugation Reactions: Phase II enzymes facilitate glucuronidation and sulfation of metabolites
The compound demonstrates a multi-faceted clearance profile:
- Hepatic Clearance
- First-pass metabolism reduces bioavailability
- Metabolites undergo biliary excretion
- Enterohepatic circulation may occur
- Renal Excretion
- Water-soluble metabolites exit via urine
- Limited unchanged drug appears in urine
- Clearance rate varies with hydration status
Laboratory studies suggest SR-9011's half-life ranges between 4-6 hours under standard conditions. The compound's metabolic profile aligns with other synthetic REV-ERB agonists, displaying predictable pharmacokinetic parameters essential for research applications.
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Practical Use Considerations for Researchers Using Swiss Chems SR-9011
Swiss Chems maintains strict protocols for SR-9011 handling and distribution to support research integrity. The ordering system processes research requests through a secure platform, with same-day shipping guaranteed for orders placed before 12 PM EST on business days (Monday through Friday).
Storage Requirements:
- Store in a cool, dry environment between 2-8°C (35.6-46.4°F)
- Keep away from direct sunlight and UV exposure
- Maintain original sealed packaging until ready for research use
- Monitor humidity levels - recommended below 65%
Laboratory Handling Guidelines:
- Use appropriate Personal Protective Equipment (PPE)
- Handle in controlled laboratory conditions
- Avoid cross-contamination with other research materials
- Document all handling procedures
Research Material Stability:
- Shelf life: 36 months from manufacture date
- Potency maintained when stored according to specifications
- Regular stability testing recommended
- Record any observed changes in physical properties
Swiss Chems provides detailed Chain of Custody documentation with each shipment, enabling researchers to track the material from synthesis to laboratory delivery. The company's dedicated research support team remains available for technical consultations regarding proper handling and storage protocols specific to ongoing research requirements.
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Advantages of Choosing Swiss Chems SR-9011 for Research Applications
Swiss Chems stands out in the research chemical industry through its dedication to product excellence and research support. The company's SR-9011 maintains consistent purity levels across batches, enabling researchers to conduct reliable experiments with reproducible results.
Research facilities benefit from Swiss Chems' innovative approach to SR-9011 formulation:
- Advanced Manufacturing Process: Utilizes cutting-edge technology to maintain compound stability
- Batch-to-Batch Consistency: Ensures experimental reproducibility
- Supply Chain Reliability: Prevents research disruptions through steady product availability
The company's commitment to research advancement is evident in their:
- Rigorous quality control measures
- Detailed chemical analysis documentation
- Responsive technical support team
Swiss Chems' SR-9011 meets the demanding standards of competitive research environments through:
- Third-party verification options
- Comprehensive product documentation
- Research-grade purity levels
These features position Swiss Chems SR-9011 as a valuable tool for researchers requiring dependable research materials for their experimental protocols.
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Visual Elements Suggestions for Article Enhancement
The integration of visual elements enhances comprehension of SR-9011's complex mechanisms and Swiss Chems' quality standards.
REV-ERB Receptor Binding Mechanism
SR-9011 → REV-ERBα/β → Gene Expression Modulation ↓ Circadian Rhythm Regulation ↓ Metabolic Pathway Activation
Comparative Chemical Properties Table
|
Property Swiss Chems SR-9011 Similar Compounds Purity |
>99% |
95-98% |
|
Half-life |
4-6 hours |
Variable |
|
Storage Stability |
36 months |
12-24 months |
|
Quality Testing |
HPLC-certified |
Varies by vendor |
Swiss Chems Quality Guarantee
- Third-party lab verification
- Money-back assurance
- Same-day shipping
- Secure packaging
Research Community Feedback
"Swiss Chems SR-9011 demonstrates exceptional consistency across batches, crucial for maintaining experimental validity." - Dr. M.K., Biochemistry Research Lead
"The comprehensive documentation and purity levels make Swiss Chems SR-9011 an ideal choice for circadian rhythm studies." - Laboratory Director, Chronobiology Institute
These visual elements serve as reference tools for researchers, providing quick access to essential information while reinforcing Swiss Chems' commitment to research excellence.
Visit Swiss Chems SR-9011 Here Today>>>. Coupon Code: SWISS69
FAQs (Frequently Asked Questions)
What is Swiss Chems SR-9011 and what makes it significant in scientific research?
Swiss Chems SR-9011 is a research chemical formulated as a synthetic REV-ERBα and REV-ERBβ agonist. It plays a crucial role in regulating circadian rhythm and metabolic pathways by modulating gene expression related to lipid and glucose metabolism, making it highly relevant for metabolic and chronobiology studies.
What are the product specifications of Swiss Chems SR-9011?
Swiss Chems SR-9011 is provided in capsule form with a dosage of 5mg per capsule, totaling 300mg of active ingredient per package (60 capsules). The product comes with packaging designed for optimal storage, boasting a shelf life of 36 months when stored under recommended conditions.
How does Swiss Chems ensure the quality and purity of their SR-9011 product?
Swiss Chems guarantees product purity through rigorous lab testing protocols, including HPLC certification. Test results are transparently available on their website, and independent verification can be conducted via certified testing facilities. Additionally, Swiss Chems offers a refund policy covering test costs, order amount, and shipping fees if the product fails verification.
What should researchers know about the pharmacokinetics and metabolism of SR-9011?
SR-9011 undergoes hepatic metabolism primarily via oxidation and conjugation pathways. Its clearance from the body involves renal and biliary excretion mechanisms. Understanding these pathways is essential for researchers to design experiments and interpret pharmacological data accurately.
What practical considerations should be taken when ordering and handling Swiss Chems SR-9011?
Researchers should note that orders placed before 12 PM EST (Monday to Friday) qualify for same-day shipping. Proper storage guidelines must be followed to maintain potency throughout the shelf life. Handling precautions specific to research chemicals should also be observed to ensure safety and integrity during use.
Why choose Swiss Chems SR-9011 for research applications over other suppliers?
Swiss Chems provides reliable research chemicals supported by innovative formulations and a consistent supply chain, which benefits experimental integrity. Their commitment to quality assurance, transparent testing, competitive pricing, and prompt shipping supports researchers in maintaining a competitive edge in their scientific investigations.